Best Practice for UI/UX to suit Laptop AND Mobile

Hi Folks
Very excited …after a few false starts … just started developing my first business mgmt portal. Have some laptop/PC users and a few smart phone users. Not the most tech savvy users so want to make the app as accessible and user friendly as possible for the SmartPhone users.
How do others approach this ?
Do you develop completely different pages or hide/load columns or even different versions of components based on device side (using tadabase’s excellent media device selection configs)
Anybody got any best practices or learnings ?

@tim.young might be a nice topic for some of your excellent teaching series.
Apologies if I missed some existing resource on this
tks
Noel D

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